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    BIODATA

    Imam Ghozali, dr.,SpAn.,Mkes.

    Lahir Bandar Lampung 3-Agustus

    Pendidikan terakhir :

    Sp. Anestesiologi (Unpad)

    Magister Kesehatan (Unpad)

    Pengalaman Kerja

    PNS DPK Tulang Bawang

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    Anesthesia

    Dr. Imam Gz. SpAn., Mkes.

    Maret, 2010

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    History of Anesthesia

    Ether synthesized in 1540 by Cordus

    Ether used as anesthetic in 1842 by Dr.

    Crawford W. Long

    Ether publicized as anesthetic in 1846

    by Dr. William Morton

    Chloroform used as anesthetic in 1853

    by Dr. John Snow

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    History of Anesthesia

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    History of Anesthesia

    Endotracheal tube discovered in 1878

    Local anesthesia with cocaine in 1885

    Thiopental first used in 1934

    Curare first used in 1942 - opened the

    Age of Anesthesia

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    Basic Principles of Anesthesia

    Anesthesia defined as the abolition of sensation

    Analgesia defined as the abolition of pain

    Triad of General Anesthesia

    need for unconsciousness

    need for analgesia

    need for muscle relaxation

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    General & Regional

    Anesthesia Intra vena

    Intra muscular

    Rectal

    Inhalasi

    BALANCE ANASTHESIA

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    PHYSIOLOGY

    PHARMACOLOGY

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    BASIC

    PHYSIOLOGY RESPIRATORY

    CENTRAL NERVUS SYSTEM

    CARDIOVASCULAR SYSTEM

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    Fundamentals of

    Anatomy &PhysiologyDr. Imam Ghozali.,SpAn.,MKes

    Unit

    1Fisiologi Respirasi

    Disampai15 Maret 2010,

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    The Respiratory System

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    What are theprimary functions of

    the respiratory system?

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    Functions of the Respiratory

    System Breathing process

    Exchange of Oxygen and Carbon

    Dioxide

    Enable speech production

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    Respiration

    external respiration- exchange of

    gases in lungs

    internal respiration- exchange of gaseswithin cells of the body organs and

    tissues

    ventilation- movement of air

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    Internal Respiration

    All cells require oxygen for metabolism

    All cells require means to remove

    carbon dioxide

    Gas exchange at cellular level

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    External Respiration

    Ventilation

    exchange of air between lungs and

    atmosphere

    Gas Exchange in pulmonary capillaries

    Breathing largely involuntary activity

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    Structures of Respiratory System

    upper respiratory tract

    nose, mouth, pharynx, epiglottis, larynx

    and trachea

    lower respiratory tract

    bronchial tree and lungs

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    Nose

    nasal cavity

    nasal septum

    mucous membrane mucus

    cilia

    olfactory receptors

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    Pharynx

    Nasopharynx

    adenoids or pharyngeal tonsils

    oropharynx

    palatine tonsils

    laryngopharynx

    larynx

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    Epiglottis

    oropharynx and laryngopharynx serve

    as a common passageway for both food

    and air epiglottis acts as a lid or flap that

    covers the larynx and trachea (airway)

    so food does not enter the lungs.

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    Larynx

    voice box

    larynx/o

    glottis (vocal apparatus)

    vocal bands or vocal cords

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    Trachea

    Windpipe or airway

    mucous membrane lining with cilia

    smooth muscle with c-shaped cartilage

    rings

    divides into two branches: bronchi

    no gaseous exchange

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    Alveoli

    air sacs

    alveolar wall membranes one

    cell thick and surrounded bycapillaries

    gaseous exchange takes place

    here

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    Right-3 lobes Left-2 lobes

    Lungs

    trachea

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    Pleura

    each lung enclosed in pleura

    parietal pleura (inner)

    visceral pleura (outer)

    pleural space or pleural cavity

    lubricating fluid

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    Diaphragm

    muscle separating chest and abdomen

    inspiration, diaphragm contracts and

    increases thoracic space

    air flows in

    expiration, diaphragm relaxes and

    decreases thoracic space

    air flows out

    phrenic nerve

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    Components of the Respiratory System

    Figure 231

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    Figure 232

    Alveolar sac

    Alveoli

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    . Hidung

    Rongga hidung memiliki

    3 fungsi utama yaitu :

    1.memanaskan udara

    2.melembabkan udara

    3.menyaring udara

    Adenoid

    Tonsil

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    2. Pangkal Tenggorokan (Laring)

    1. Tersusun dari lempengan-lempengan tulang rawan.

    2. Terdapat GLOTIS yaitu celah penghubung trakea - faring,

    3. Terdapat EPIGLOTIS yaitu katup pengarur jalannya udara dan makanan.

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    Divisions of the Pharynx

    Nasopharynx

    Oropharynx

    Laryngopharynx

    A f h L

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    Anatomy of the Larynx

    Figure 234

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    3. Batang Tenggorokan (Trakea)

    1. Tersusun dari cincin tulang rawan berbentuk pipa

    2. Terletak di depan kerongkongan

    3. Bagian dalam licin dan berlendir terdapat jaringan epitelyangtersusun dari sel-sel bersilia yang berfungsi menahan debu

    dan kotoran.

    Trakea

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    4. Bronkus & 5. Bronkiolus

    1. Bronkus = penghubung trakea dengan paru-paru.

    2. Ada 2 bagian yaitu bronkus kiridan bronkus kanan.

    3. Bronkus bercabang menjadi BRONKIOLUS.

    4. Pada ujung BRONKIOLUSterdapat kantung udara yang disebut

    ALVEOLUS.

    * Dinding alveolus terdapat banyak pembuluh kapiler darahtempat terjadinya pertukaran gas O2 dan CO2.

    Alveolus Pembuluhkapiler darah

    Bronkus

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    . Paru-Paru (Pulmo)

    1. Terletak di dalam rongga dada diatas diafragma.

    2. Terdapat BRONKUS, BRONKIOLUS, ALVEOLUS.

    DIAFRAGMA = sekat yang membatasi rongga dadadengan

    rongga perut.

    PLEURA = selaput elastis pembungkus paru-paru.

    Gross Anatomy of the Lungs

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    Figure 237

    Gross Anatomy of the Lungs

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    The Right Lung

    Has 3 lobes: superior,

    middle, and

    inferior

    separated by

    horizontal and

    oblique fissures

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    The Left Lung

    Has 2 lobes:

    superior and

    inferior

    are separated

    by an obliquefissure

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    Relationship between Lungs and Heart

    Figure 238

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    Bronchitis

    Inflammation of bronchial walls:

    causes constriction and breathing

    difficulty

    The Bronchioles

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    Figure 2310

    The Bronchioles

    Bronchodilation

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    Bronchodilation Dilation of bronchial airways

    Caused by sympathetic ANS activation Reduces resistance

    Bronchoconstriction Constricts bronchi

    Caused by:

    parasympathetic ANS activation

    histamine release (allergic reactions)

    Asthma Excessive stimulation and bronchoconstriction

    Stimulation severely restricts airflow

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    Surfactant Is an oily

    secretion Contains

    phospholipids and

    proteins

    Coats alveolarsurfaces and

    reduces surface

    tension

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    Figure 238

    Pleural Cavities and Pleural Membranes

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    Pleural Cavities and

    Pleural Membranes 2 pleural cavities:

    are separated by the mediastinum

    Each pleural cavity: holds a lung

    is lined with a serous membrane (the

    pleura)

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    The Pleura

    Consists of 2 layers:

    parietal pleura

    visceral pleura

    Pleural fluid:

    lubricates space between 2 layers

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    3 Processes of

    External Respiration1. Pulmonary ventilation(breathing)

    2. Gas diffusion:

    across membranes and capillaries

    3. Transport of O2and CO 2:

    between alveolar capillaries

    between capillary beds in other tissues

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    Mekanisme Pernapasan

    Dalam pernapasan ada 2 siklus1.Menghirup (INSPIRASI)

    2.Mengeluarkan (EKSPIRASI)

    M k i P

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    Mekanisme Pernapasan

    Pernapasan Dada / Tulang Rusuk

    Mekanisme Menghirup Udara (INSPIRASI)

    Otot antar tulang rusuk berkontraksi sehingga:

    1. Rongga dada membesar,

    2. Tekanan udara dalam paru mengecil,

    3. Udara masuk dari luar ke dalam paru-paru.

    Mekanisme Mengeluarkan Udara (EKSPIRASI)

    Otot antar tulang rusuk berelaksasi sehingga:

    1. Rongga dada mengecil,

    2. Tekanan udara dalam paru membesar

    3. Udara keluar dari paru-paru

    M k i P

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    Mekanisme Pernapasan

    Pernapasan Perut

    Mekanisme Menghirup Udara (INSPIRASI)

    Otot diafragma kontraksi sehingga:

    1. otot diafragma mendatar,

    2. rongga dada membesar

    3. tekanan udara dalam paru mengecil,

    4. udara dari luar masuk kedalam paru-paru

    Mekanisme Mengeluarkan Udara (EKSPIRASI)

    Otot diafragma relaksasi sehingga:

    1. otot diafragma kembali melengkung ke atas,

    2. rongga dada mengecil

    3. tekanan udara dalam paru meningkat,

    4. udara keluar paru-paru

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    Volume Kapasitas Paru-Paru

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    Volume & Kapasitas Paru-Paru

    Volume paru-paru= 5-6 liter

    Terdiri dari :

    Volume Tidal sebanyak 0,5 liter hasil pernafasan normal

    Volume Cadangan Inspirasi = volume udara ekstrayang dapat di inspirasi setelah volume tidal, bisa mencapai

    3 liter

    Volume Cadangan Ekspirasi = volume udara ekstra

    yang dapat di ekspirasi setelah ekpirasi normal, bisa

    mencapai 1,1 liter. Volume Residu adalah = volume udara yang masih

    tetap berada di paru-paru sekalipun sudah dilakukan

    ekspirasi kuat, bisa mencapai 1,2 liter.

    0,5 + 3 + 1,1 + 1,2 = 5,8 liter

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    Kapasitas Paru-Paru

    Kapasitas Paru-paruadalah aplikasi/kombinasi dari

    dua jenis volume paru-paru :

    Kapasitas Inspirasi = VT+ VCI Kapasitas Residu Fungsional = VCE+ VR

    Kapasitas Vital =VCI+ VT+ VCE

    Kapasitas Paru-Paru Total = Kapasitas Vital + VR

    Adi memiliki VT = 0,6; VCI = 3,2; VCE = 1,1; VR = 1

    Hitung:

    1. Kapasitas Inspirasi 3. Kapasitas Vital

    2. Ka asitas Residu Fun sional 4. Ka asitas Total

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    Frekuensi Pernapasan

    Cepat lambatnya pernapasan dipengaruhi oleh:

    1. Umur

    Makin tua makin lambat, karena butuh sedikit

    energi

    2. Jenis Kelamin

    Laki-laki lebih butuh banyak energi dibandingperempuan

    3. Suhu Tubuh Suhu tubuh turun, O2makin butuh banyak untuk

    meningkatkan metabolisme

    4. Posisi Tubuh / Aktivitas

    Makin aktif tubuh makin banyak butuh O2

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    Mekanisme Pertukaran

    O

    2

    dan CO

    2

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    Mekanisme Pertukaran O2 dan

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    Mekanisme Pertukaran O2danCO2

    Mechanisms of Pulmonary Ventilation

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    Figure 2314

    Mechanisms of Pulmonary Ventilation

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    Respiration

    Causes volume changes that create

    changes in pressure

    Volume of thoracic cavity changes: with expansion or contraction of

    diaphragm or rib cage

    The Respiratory Muscles

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    Figure 2316a, b

    e esp ato y Muscles

    The Respiratory Muscles

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    The Respiratory Muscles

    Figure 2316c, d

    3 Muscle Groups of Inhalation

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    p1. Diaphragm:

    contraction draws air into lungs

    75% of normal air movement

    2. External intracostal muscles:

    assist inhalation

    25% of normal air movement

    3. Accessory musclesassist in elevating

    ribs:

    sternocleidomastoid serratus anterior

    pectoralis minor

    scalene muscles

    Respiratory Performance and Age

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    Respiratory Performance and Age

    Figure 2328

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