Reactions 1329 - 27 Nov 2010

Pregabalin

Drug eruption: case reportA 27-year-old woman with systemic lupus

erythematosus and nephrogenic systemic fibrosis (NSF)presented with a 1-week history of a red, pruritic rash onher legs, which had started 2 days after starting pregabalin[dosage, route and therapeutic indication not stated].Examination revealed a few scattered erythematouspapules on her legs as well as skin-coloured induratedplaques on the extremities. Punch biopsies were consistentwith NSF and osseus metaplasia with a superimposed drugeruption. Pregabalin was withdrawn and the eruptionresolved.Berk DR, et al. Osseous metaplasia late in the course of nephrogenic systemicfibrosis. Dermatology Online Journal 16: 3, No. 8, Aug 2010 - USA 803044432

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Reactions 27 Nov 2010 No. 13290114-9954/10/1329-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved