POTENSI PEMBERIAN PERASAN BUAH NONI (Morinda citrifolia) TERHADAP KEMATIAN LARVA Aedes aegypti INSTAR IIIGorbi MarindraABSTRAKLatar belakang. Nyamuk Aedes aegypti merupakan vektor penyakit seperti demam berdarah dengue. Aedes aegypti memerlukan perhatian khusus, karena berhabitat terutama di negara tropis, seperti Indonesia. Upaya pemberantasan nyamuk Aedes aegypti bisa dilakukan dengan berbagai cara, salah satunya adalah dengan pemberantasan larva. Pengendalian larva bisa dilakukan menggunakan kimia maupun alami. Kimia bisa menggunakan Abate, sedangkan alami bisa menggunakan bahan dari alam. Salah satunya adalah menggunakan buah noni.Tujuan. Penelitian ini bertujuan untuk membuktikan adanya potensi mematikan dari buah noni dalam bentuk perasan terhadap kematian larva instar III Aedes aegypti.Metoda. Rancangan penelitian ini merupakan penelitian eksperimental murni dengan rancangan Post Test Only Control Group Design. Sampel larva Aedes aegypti instar III diperoleh dari laboratorium Entomologi ITD (Institute of Tropical Disease), Surabaya. Sampel harus memenuhi kriteria inklusi dan ekslusi. Penelitian ini menggunakan 9 kelompok perlakuan dengan 3 kali pengulangan. Besar sampel masing-masing kelompok sebanyak 20 larva. Semua kelompok diberi perlakuan sama, yaitu larva tidak diberi makan selama 24 jam sejak terpapar perasan buah noni. Hasil. Analisa data dilakukan dengan uji Mann Whitney dan uji t satu sampel dengan nilai = 0,05. Uji LC50 didapati hasil= 55,34%, sedangkan uji LC90 didapati hasil= 63,84%. Kesimpulan. Hasil penelitian menunjukkan bahwa buah noni memiliki potensi mematikan larva instar III Aedes aegypti. Kata kunci : Perasan, buah noni, larva Aedes aegypti instar III, kematian larva.POTENTIAL EFFECTS OF NONI FRUIT (Morinda citrifolia) SQUASH AS A POTENTIAL NATURAL LARVICIDAL INSTAR III AGENT AGAINST Aedes aegypti Gorbi MarindraABSTRACTBackgrounds. The mosquito spesies Aedes aegypti is a vector of dengue fever. Aedes aegypti requires a special attention, especially because its habitat is mainly in tropical countries, such as Indonesia. Eradication efforts can be made with many measures, such as the use of larvicidal agents. Eradication of larvae methods can use both chemically or naturally. Chemically by means of Abate , naturally by products of nature. For example is noni fruit.Aims. This experiment is conducted to proof that noni fruit squash has a potential as an larvicidal agent against Aedes aegypti larvae instar III.Methods. Design of this research is pure experimental with Post Test Only Control Group Design. Aedes aegypti instar III larvae sample is collected from Entomology laboratorium of ITD (Institute of Tropical Disease), Surabaya. Sample must fulfill both inclusion as well as exclusion criteria. This experiment uses 9 different groups with 3 times replication. Each group has each 20 larvae. All groups are given the same conduct, which is, the larvae isnt fed dor 24 hours after noni fruit exposure. Results. Data analysis uses Mann Whitney test and one sample t-test with = 0,05. The result value of LC50= 55,34%, whereas LC90 value= 63,84%. Conclusion. The results of the experiment shows a promising result that the noni fruit squash has a potential as a larvicidal agent for Aedes aegypti instar III. Key words : Squash, noni fruit, larvae, Aedes aegypti, instar III, larvae death.