Cetuximab
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Reactions 1078 - 19 Nov 2005 Cetuximab Skin eruptions: case report A 48-year-old man received IV cetuximab for metastatic colorectal cancer [dosage, duration of treatment and time to reaction onset not stated] and developed a skin eruption consisting of sterile papules and pustules with an adherent yellow crust on his chest, back and face. The crust on his face was debrided and hydrocortisone cream was applied to the right side of his face and tazarotene cream to the left. One week later, the right side of his face showed greater improvement. Author comment: "This rash is a characteristic effect of therapy with [epidermal growth factor receptor] inhibitors and is associated with an improved outcome." Moss JE, et al. Cetuximab-associated acneiform eruption. New England Journal of Medicine 353: e17, No. 19, 10 Nov 2005 - USA 801002525 1 Reactions 19 Nov 2005 No. 1078 0114-9954/10/1078-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
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Transcript of Cetuximab
Reactions 1078 - 19 Nov 2005
Cetuximab
Skin eruptions: case reportA 48-year-old man received IV cetuximab for metastatic
colorectal cancer [dosage, duration of treatment and time toreaction onset not stated] and developed a skin eruptionconsisting of sterile papules and pustules with an adherentyellow crust on his chest, back and face. The crust on his facewas debrided and hydrocortisone cream was applied to theright side of his face and tazarotene cream to the left. Oneweek later, the right side of his face showed greaterimprovement.
Author comment: "This rash is a characteristic effect oftherapy with [epidermal growth factor receptor] inhibitorsand is associated with an improved outcome."Moss JE, et al. Cetuximab-associated acneiform eruption. New England Journal ofMedicine 353: e17, No. 19, 10 Nov 2005 - USA 801002525
1
Reactions 19 Nov 2005 No. 10780114-9954/10/1078-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
